My postulate is that our genome dictates how our neurons function, including which chemicals they secrete and when. When a person takes drugs or abuses substances, this interferes with the normal activity of neurons and triggers changes in their signaling. Over time, these changes can alter neuronal circuits and brain function, contributing to neuroplasticity. The brain is an electrochemical organ, using electricity to send rapid signals along neurons and chemicals (neurotransmitters) to transmit messages across the gaps (synapses) between them. This system powers thought, memory, and action, with around 86–100 billion neurons creating complex, high-speed, and energy-consuming networks. The electricity and chemicals can work smoothly and interchangeably. Electrical brain stimulation is similar to taking antidepressants.
